DIETARY-PHYTOCHEMICAL MEDIATED REVERSION OF CANCER-SPECIFIC SPLICING INHIBITS WARBURG EFFECT IN HEAD AND NECK CANCER

Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer

Abstract Background The deregulated alternative splicing of key glycolytic Rangehood Globe enzyme, Pyruvate Kinase muscle isoenzyme (PKM) is implicated in metabolic adaptation of cancer cells.The splicing switch from normal PKM1 to cancer-specific PKM2 isoform allows the cancer cells to meet their energy and biosynthetic demands, thereby facilitati

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Identification of two new repetitive elements and chromosomal mapping of repetitive DNA sequences in the fish Gymnothorax unicolor (Anguilliformes: Muraenidae)

Muraenidae is a species-rich family, with relationships among genera and species and taxonomy that have not been completely clarified.Few cytogenetic studies have been conducted on this family, and all of them showed the same diploid Saw Blades chromosome number (2n=42) but with conspicuous karyotypic variation among species.The Mediterranean moray

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The Effectiveness Of The Hope Family Program As Poverty Reduction Effort (Case Study In Pringsewu District, Lampung Province)

The problem of poverty is still an Tubing important issue in Indonesia.The Indonesian government has made various efforts to tackle the problem of poverty, one of which is through the Family Hope Program (PKH), which is a cluster of policies based on social assistance and protection in the form of meeting the basic needs of health and education for

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